FACILITATING THE BIOLOGICAL WORKFLOW

NovoNexile develops regenerative technologies of the next generation to innovate the clinical workflow and improve the patients biologic response.

 

Biomaterials are crucial in modern regenerative procedures. In most procedures they are essential to restore the structure and function of damaged or dysfunctional tissue. Different indications and patient conditions can result in differences in the regenerative capacity of a tissue to heal and regenerate. With our innovations we address the limited ability of traditional biomaterials to respond to individual requirements of the biologic indication and clinical use that can lead to compromised clinical outcomes.

 

 

 

 

 

 

 

 

ExtraCellular Matrix (ECM): Foundation for Regeneration

The Extracellular Matrix (ECM) is the foundation of different tissues of the human body. Tissue formation, function and regeneration after damage are all governed by a well synchronized temporal and spatial interplay between cells and the ECM. The type and quality of the ECM represents a crucial element in tissue healing and true regeneration.

REPAIR - THE NATURAL TISSUE RESPONSE TO DAMAGE

Only few tissues in adult humans have preserved their capacity to regenerate. Most tissues however respond to damage by an acute inflammation. This results in a faster wound closure and to scar tissues with reduced functionality.

 

 

 

 

NovoNexile focuses on bioengineered extracellular matrices that are tailored to the biologic requirements of the individual tissue and clinical indication. Combined with a precise and fast application, NovoNexile provides clinicians with one of the most innovative tools to optimize the clinical outcome of regenerative procedures.

 

 

 

 

 

 

SYNMATRIX – DESIGNED TO INDUCE INDICATION SPECIFIC REGENERATION

SYNMATRIX is a bioengineered synthetic matrix scaffold containing 3 design elements for induced and guided regeneration:

 

(1) ligands for cell adhesion,

(2) a mechanism for temporal and spatially controlled matrix dissolution and

(3) morphogenic signals to attract progenitor cells and stimulate their differentiation into

     a regenerative pathway.

 

 

 

 

 

 

 

SYNMATRIX is based on biofunctional crosslinkable polymers that are able to form a bioinert and biodegradable hydrogel in situ and within seconds after application.

 

SYNMATRIX is a versatile technology platform. Its composition can be fine tuned to adapt to meet the biological requirements of the target indication. Its orthogonal and specific crosslinking properties allow the incorporation and release of bioactive elements to stimulate healing and regeneration of various tissues.

 

 

 

 

 

 

 

 

SYNMATRIX –PRECISELY ADAPTED TO INDIVIDUAL REQUIREMENTS

OF CLINICAL THERAPY

Design und Realisation: www.mfaustgrafikdesign.de

SYNMATRIX offers a broad design space and can be formulated into tissue matrices for various applications. SYNMATRIX is applied as a flowable matrix that crosslinks and solidifies to a hydrogel synchronized to the requirements of the clinical application.